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The following case studies do not represent implemented treatment programs. They are protocols developed by students in the course of their studies, and should be taken as examples only.

Note - Anyone suffering from the conditions described below should seek advice from a primary health care practitioner. No responsibility is taken for any individual attempting to use the treatments described in these studies.


Woman 66 y.o.a suffers from osteoarthritis. She has broken her leg-lower 3 years ago and found it very difficult to do any exercise, yet she persevered with walking 4 times weekly until recently she developed back pain and great muscle soreness in her shoulders and arms. Her doctor has given a diagnosis of Ankylosisng Spondylitis, but is carrying out further tests. The anti-inflammatory drugs are paying havoc with her digestion. Her diet consists of meat and vegetables, heavily salted, 3-5 coffees, and 3-5 wines daily.


Definitions

Osteoarthritis is a degenerative joint disease often referred to as rheumatism1. It is most often associated with joints subject to excessive wear and tear (eg the weight bearing joints of the knees, hip ankle and spine). A wearing and erosion of the protective cartilage is combined with inflammatory attack to lead to progressive breakdown of the joint, with pain and disability2.

Ankylosing Spondylitis is a painful progressive rheumatoid disease involving the spine and sacro-illiac joints. The basic lesion is synovitis, leading to calcification of the spinal ligaments. It is more prevalent in men than woman1.

Mitigating Factors – Ankylosing Spondylitis

  • 10-20% of patients with inflammatory bowel disease get ankylosing spondylitis1
  • Concentrations of serum IgA and secretory IgA (presumably from bowel mucosal origin) are raise in spondylitis. This would suggest the presence of a sort of bowel inflammation1
  • Bowel infection are associated with reactive arthropathy which in turn can be complicated with inflammatory spinal disease1
  • The disease can be precipitated by certain micro-organisms that seemingly lie dormant in the individual. Klebsiella has been associated with the destruction of HLA-B27 positive lymphocytes of patients with ankylosing spondylitis1
  • Serum vitamin E levels were lower than normal in these patients. Supplementation resulted in the relief of pain. (Alpha and gamma tocopherol should be used.)1

Treatment Goals

  • Heal and seal the gut
  • Treat infection by micro-organisms
  • Encourage remineralisation of the bone
  • Reduce pain
  • Increase range of movement
  • Excrete waste product
  • Improve integrity of cartilage

Dietary Considerations

Foods to Reduce Foods to Increase
foods that increase acidity especially red meat, and refined carbohydrates.

Nightshades (potato, tomato, etc)

Processed foods and those with additives

Coffee & Wine (Down to one cup/glass per day and none if possible)

Attempt to use cleansing/detoxifying food, and organic product to reduce build up of toxins.

Eat foods that are high in EFAs such as fish

Tripe, oats, shark fin soup, mussels and calf trachea [Oseicki]. These are high in proteoglycans useful in building up cartilage.

Whole grain cereals, hard nuts – high in silicon which is important in bone homeostasis [Oseicki]

Include ginger in cooking

Dietary Supplements

Vitamins C, D, E, B9, B12, B5, B3

Minerals Copper Chelate topically1

Probiotics to increase presence of bowel flora

Glucosamine (enhances cartilage repair)1

Life Style

Low stress exercise – walking and especially swimming is possible.

As and when reduce intake of anti-inflammatory drugs these will slow down cartilage repair.

Herbal Protocol

I would probably proceed with a three formulas addressing the problem from a number of fronts:

  1. enhance function of the gut addressing inflammation and infection;
  2. address arthritis and spondylitis;
  3. provide a night time brew to aid sleep and reduce pain at night.

Naturally I would consider the patients ability to afford the medication, and her likely compliance, before using so many mixtures. If this proved to be a problem, I would reduce the number of mixes by (at least) combining the gut mix with the arthritis/spondylitis mix. I might also consider the use of Boswellia serrata tablets.

Heal & Seal Mix

The classes I would use include:

Astringents – to heal the walls and lining of the GIT

Antimicrobials – to address GIT infection

Demulcents – to sooth and heal the gut wall

Gastric acid normaliser – to aid with digestion, pain, dyspepsia

Hepatic/Bitter – to normalise liver function/aid elimination/aid digestion

Antispasmodics – to reduce gut tension and aid in relaxation

Filipendula ulmaria – acid normaliser, anti-inflammatory 40
Silybum marianum – first stage liver detox 40
Hydrastis canadensis – antimicrobial, hepatic, astringent, antiinflammatory 30
Chamomilla recutita – antispasmodic, antiinflammatory, antiseptic 40
Trigonella foenum-graecum – anti-inflammatory, demulcent, digestive tonic, healing 40
Zingiber officinalis – anti-inflammatory, carminitive, adjuvant 10
  200

Dosage – start low (2ml tds) to avoid over-addressing liver detox then build over the next few weeks to 5mls tds. Probably taken 30 minutes prior to meals.

Ulmus fulva (1 tablespoon in warm water) would also be suggested 30 minutes before meals.

Arthritis & Spondylitis Mix

The classes I would use include (care must be taken not to overdo the detoxification regime):

Alteratives – to aid in the elimination of toxins from the system

Antiinflammatory – to reduce inflammation as it occurs and relieve some pain

Analgesic – to relieve pain

Immunostimulants – to enhance the immune system and aid in elimination of infection

Circulatory Stimulants – to improve circulation to the affected areas and remove metabolic wastes

Antispasmodics – to reduce muscle tension around joints that could be contributing to the pain

(Possibly) Immuno-depressants – to normalise overactive parts of the immune system

Echinacea angustifolia – immunostimulant, anti-inflammatory, alterative, antimicrobial 35
Salix alba – anti-inflammatory, analgesic 40
Uncaria tomentosa – immunostimulant, antioxidant, anti-inflammatory 30
Harpagophytum procumbens – anti-inflammatory, analgesic, bitter, anti-rheumatic (esp. large joints) 60
Cimicifuga racemosa –alterative, antispasmodic 30
Zingiber officinalis –circulatory stimulant, anti-inflammatory, spasmolytic 5
  200

Also may add Tylophera indica in drop doses as immuno-depressant.

Dosage – 5mls tds to be taken between meals when stomach acid at lowest.

Night time mix

To aid with sleep I would suggest the following prior to retiring:

Valeriana officincalis – sedative, spasmolytic, mild analgesic 30
Withania somnifera – nervine sedative, anti-inflammatory, spasmolytic, adaptogenic 80
Viburnum opulus – spasmolytic, sedative 40
Piscidia erythrina – analgesic, sedative 50
  200

Dosage – 5mls tds half an hour prior to retiring.

Also suggest use of external rubefacient rubs such as Ruta graveolens, and Capsicum annuum for pain relief.

Cautions and Contraindications3

General caution if patient is sensitive to salicylates.

Hydrastis canadensis Pregnancy (not likely to be a problem), Hypertension
Trigonella foenum-graecum Pregnancy
Zingiber officinale Persons with gallstones
Uncaria tomentosa Not enough information is available to state its safety with certainty
Harpagophytum procumbens Gastric and duodenal ulcers
Cimicifuga racemosa Pregnancy and lactation; large doses may cause nausea vomiting etc
Withania somnifera Pregnancy; may potentiate the effects of barbituates
Piscidia erythrina To be used with care 2

References

1. Osiecki H, The Physician’s Handbook of Clinical Nutrition – 5th Edition, Bioconcepts Publishing, Queensland, 1998.

2. Mills, S., The Complete Guide to Modern Herbalism, Thorsons, Great Britain, 1994.

3. McGuffin, M., Hobbs, C., Upton, R., Goldberg, A., American Herbal Products Association - Botanical Safety Handbook, CRC Press, 1997.

Copyright © The Australian Naturopathic Network 1998-2002. All rights reserved. 
Revised: May 18, 2002 .